Beyond HbA1c: Defining the Modern Treatment Goals in T2D Contemporary T2D management is no longer defined by achieving HbA1c targets alone. The ADA Standards of Care 2026 advocate a person centred approach, recommending that therapeutic decisions be guided by individualized glycaemic and weight goals, the…
Kidney disease ends here. A £5.2 million network, supported by the Stoneygate Trust and Kidney Research UK, has been created to help more donated kidneys reach patients waiting for life-changing transplants. Working across five leading transplant centres in Cambridge, London, Oxford,…
At EAU 2026, Dr. Buteau and colleagues aimed to demonstrate that 68Ga-PSMA-11 PET/CT could reduce patients requiring biopsy and limit biopsy to targeted cores, without significantly decreasing significant prostate cancer diagnosis. Significant prostate cancer was defined as Gleason score 3+4 (≥10% pattern…
Will PSMA PET ever replace prostate biopsy? Before an irreversible treatment, clinicians need more information than a binary determination of whether clinically significant prostate cancer is present. A tissue diagnosis provides answers regarding: False positive results of PSMA PET imaging…
Alberto Briganti and Yao Zhu debate whether PSMA PET can replace prostate biopsy. Dr. Briganti argues biopsy remains necessary even with positive PSMA findings, since imaging cannot capture tumor volume, grading heterogeneity, variant histology, or transcriptomic signatures, and warns that…
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Bioengineer.org In addition to evaluating lineage-tracing methodologies, the review organizes candidate molecular mechanisms into an explicit causal signaling hierarchy centered on transforming growth factor-beta 1 and Smad3, acting upstream of Src and Pou4f1 pathways. The authors evaluate this regulatory axis within the…
Di Zhao presents preclinical work on B7-H3, an overexpressed immune checkpoint molecule in prostate cancer that rises with disease progression and is associated with worse outcomes. Using the antibody-drug conjugate DS-7300a, now in phase 3 trials, Dr. Zhao found p53 loss confers resistance…
People diagnosed with cardiovascular disease should also be checked for chronic kidney disease, according to new European guidelines. The recommendation aims to find kidney problems early enough for doctors to adjust care and reduce the risk of complications affecting both…
BIRMINGHAM, Ala. (WBRC) - Ruger Ennis, 10, of Ardmore, was recognized Wednesday as an ambassador for the Alabama Kidney Foundation. Ruger’s search for a kidney donor inspired people to step forward as potential donors and brought a community together around his family.
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