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Triplex-purified minicircle DNA restores frataxin in Friedreich’s ataxia cells and mice
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Invisible changes in our cells may shape health and disease
Media Contact: Leila R. Gray - 206-475-9809, [email protected] The genetic material inside a person's cells is not identical throughout the body. Because cells pick up changes throughout life, every one of us has a patchwork of cells with a slightly different genetic sequence,…
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FLC-like gene shapes hormone balance in Japanese apricot winter buds
The team had previously identified PmFLC-like as a gene that is highly expressed in Prunus mume flower buds during autumn and winter. The gene is conserved as a single copy across several Prunus fruit tree species, a pattern that suggested…
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Red Sea fish teeth reveal convergent evolution and selection on tooth genes
Together, the findings highlight the interplay between dietary ecology, tooth morphology, and molecular evolution in teleost fishes. The combination of ultrastructural imaging and genome-wide selection scans provides a framework for connecting form, function, and genes in a species-rich marine ecosystem…
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Researchers discover the clever tactics octopuses use to fit through holes much smaller than their bodies
An octopus has no bones, so it can squeeze through a gap far narrower than its body. It often does that in the wild to escape predators and to catch prey. In a recent study, scientists have deciphered the exact,…
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New genomic tools improve detection of rare DNA changes
WashU Medicine researchers have verified the accuracy of genetics tools to correctly identify all the rare DNA changes that make up an individual's genomic mosaic, paving the way to understanding these variants' impact on health and disease. Researchers at Washington…
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University of Santiago de Compostela and Lactalis España launch dairy cattle management guide
Dairynews.today University of Santiago de Compostela and Lactalis España launch dairy cattle management guide The event took place on Thursday at Casa Cortés, a farm in Mesía, a municipality in the Órdenes district of A Coruña province. The presentation…
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Genome study reveals shared genetic roots of fibrotic diseases
The team identified 654 genome-wide significant associations between genetic variants and fibrotic traits. Of these, 139 represent previously unreported associations for their respective traits, expanding the catalog of known genetic risk factors for fibrotic conditions. The findings identify novel genetic associations and…
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Researchers Establish Best Methods to Measure Genetic Variation Within the Body
WashU Medicine researchers have verified the accuracy of genetics tools to correctly identify all the rare DNA changes that make up an individual’s genomic mosaic, paving the way to understanding these variants’ impact on health and disease. Newswise — Researchers at…
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How lipids influence amyloid aggregation in cerebral amyloid angiopathy (CAA)
Although CAA and Alzheimer’s disease share Aβ-related pathology, the structural characteristics of Aβ aggregates in CAA and how they change as the disease progresses remain poorly understood. Conventional methods that depend on fibrils extracted from brain tissue may fail to…
Genetics & Genomics
DNA sequencing, CRISPR edits, population genetics, and trait mapping.
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